Abstract□A study was performed to compare the anticancer effects of Korean and Chinese red ginseng roots. The whole crude extracts or chloroform, methanol and acetone fractions of the crude extracts were added in the culture medium of three
cancer
cell
lines, a mouse leukemia cell line (P388), a human colon carcinoma cell line (HT-29) and a human rectal carcinoma cell line (HRT-18), to screen the growth inhibition effects.
The results are summerized as follows:
1. Crude extracts of both Korean and Chinese red ginseng roots inhibited the proliferation of all the three cancer cell lines tested in a dose dependent manner. However, the growth inhibition effects of Korean red ginseng extracts were
significantly
greater than that of Chinese red ginseng.
2. An acetone fraction showed the greatest antiproliferative effects among the whole crude extracts, chloroform, methanol and acetone fractions of the crude extracts.
3. These results suggest that the active antiproliferative components of the crude extracts are present mostly in the acetone fraction.
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